In vitro characterization of the antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle Disease Virus

Newcastle Disease Virus (NDV) causes a serious infectious disease in birds that results in severe losses in the worldwide poultry industry. Despite vaccination, NDV outbreaks have increased the necessity of alternative prevention and control measures. Several recent studies focused on antiviral comp...

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Autores principales: Elizondo González, Regina, Cruz Suárez, Lucía Elizabeth, Ricque Marie, Denis, Mendoza Gamboa, Edgar, Rodríguez Padilla, Cristina, Trejo Ávila, Laura M.
Formato: Artículo
Lenguaje:inglés
Publicado: BioMed Central Ltd. 2012
Materias:
Acceso en línea:http://eprints.uanl.mx/11147/1/1743-422X-9-307.pdf
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author Elizondo González, Regina
Cruz Suárez, Lucía Elizabeth
Ricque Marie, Denis
Mendoza Gamboa, Edgar
Rodríguez Padilla, Cristina
Trejo Ávila, Laura M.
author_facet Elizondo González, Regina
Cruz Suárez, Lucía Elizabeth
Ricque Marie, Denis
Mendoza Gamboa, Edgar
Rodríguez Padilla, Cristina
Trejo Ávila, Laura M.
author_sort Elizondo González, Regina
collection Repositorio Institucional
description Newcastle Disease Virus (NDV) causes a serious infectious disease in birds that results in severe losses in the worldwide poultry industry. Despite vaccination, NDV outbreaks have increased the necessity of alternative prevention and control measures. Several recent studies focused on antiviral compounds obtained from natural resources. Many extracts from marine organisms have been isolated and tested for pharmacological purposes, and their antiviral activity has been demonstrated in vitro and in vivo. Fucoidan is a sulfated polysaccharide present in the cell wall matrix of brown algae that has been demonstrated to inhibit certain enveloped viruses with low toxicity. This study evaluated the potential antiviral activity and the mechanism of action of fucoidan from Cladosiphon okamuranus against NDV in the Vero cell line
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spelling eprints-111472024-03-07T16:17:29Z http://eprints.uanl.mx/11147/ In vitro characterization of the antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle Disease Virus Elizondo González, Regina Cruz Suárez, Lucía Elizabeth Ricque Marie, Denis Mendoza Gamboa, Edgar Rodríguez Padilla, Cristina Trejo Ávila, Laura M. SH Acuacultura / Pesca Newcastle Disease Virus (NDV) causes a serious infectious disease in birds that results in severe losses in the worldwide poultry industry. Despite vaccination, NDV outbreaks have increased the necessity of alternative prevention and control measures. Several recent studies focused on antiviral compounds obtained from natural resources. Many extracts from marine organisms have been isolated and tested for pharmacological purposes, and their antiviral activity has been demonstrated in vitro and in vivo. Fucoidan is a sulfated polysaccharide present in the cell wall matrix of brown algae that has been demonstrated to inhibit certain enveloped viruses with low toxicity. This study evaluated the potential antiviral activity and the mechanism of action of fucoidan from Cladosiphon okamuranus against NDV in the Vero cell line BioMed Central Ltd. 2012 Article PeerReviewed text en http://eprints.uanl.mx/11147/1/1743-422X-9-307.pdf http://eprints.uanl.mx/11147/1.haspreviewThumbnailVersion/1743-422X-9-307.pdf Elizondo González, Regina y Cruz Suárez, Lucía Elizabeth y Ricque Marie, Denis y Mendoza Gamboa, Edgar y Rodríguez Padilla, Cristina y Trejo Ávila, Laura M. (2012) In vitro characterization of the antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle Disease Virus. Virology journal, 9 (307). pp. 1-9. ISSN 1743-422X http://www.virologyj.com/content/9/1/307
spellingShingle SH Acuacultura / Pesca
Elizondo González, Regina
Cruz Suárez, Lucía Elizabeth
Ricque Marie, Denis
Mendoza Gamboa, Edgar
Rodríguez Padilla, Cristina
Trejo Ávila, Laura M.
In vitro characterization of the antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle Disease Virus
thumbnail https://rediab.uanl.mx/themes/sandal5/images/online.png
title In vitro characterization of the antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle Disease Virus
title_full In vitro characterization of the antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle Disease Virus
title_fullStr In vitro characterization of the antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle Disease Virus
title_full_unstemmed In vitro characterization of the antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle Disease Virus
title_short In vitro characterization of the antiviral activity of fucoidan from Cladosiphon okamuranus against Newcastle Disease Virus
title_sort in vitro characterization of the antiviral activity of fucoidan from cladosiphon okamuranus against newcastle disease virus
topic SH Acuacultura / Pesca
url http://eprints.uanl.mx/11147/1/1743-422X-9-307.pdf
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